ABOUT US
Molecular glues and protein–protein interaction stabilizers have produced some of the most important therapies in oncology and immunology. They work by inducing proximity: holding two proteins in a productive embrace. Outside of biologics, nearly every example has been found by accident or through derivatization of natural products. The bottleneck isn’t biology or clinical translation — it’s the inability to intentionally screen for glues at scale.
At Delphini, we use the DELSTAR™ platform and utilize the power of DNA encoded libraries and proximity induced technology to permanently encode a binding event between two targets into the DNA … to find molecules that induce proximity between the targets.
